Here's a quick sampling from a random group of top sites:
stackoverflow.com (googleapis.com), kickstarter.com (googleapis.com), cnn.com (their own cdn), businessinsider.com (jquery.com), foxnews.com (their own cdn), nbcnews.com (aspnetcdn.com), espn.com (espncdn.com), tumblr.com (secure.assets.tumblr.com), lastfm.com (googleapis.com), lyricsmode.com (googleapis.com), reference.com (sfdict.com, cdn for ask etc), qz.com (googleapis.com), theverge.com (googleapis.com), ehow.com (googleapis.com), wikia.com (googleapis.com), chacha.com (googleapis.com)
No idea if it's all linked up, but it means that using alternative search engines doesn't really matter if you still visit Google-enhanced destinations.
Use of these (to serve static content) reduces your server traffic/load and gives a faster response times to users in different geographical regions.
Doesnt seem like a really big argument against, especially considering the size of the library for the first non-cache hit