Ask HN: Guide for experienced programmers interested in web app development?

You may already know this but, I'd say choosing your platform would be a good first step, Ruby, Python, C#, Java, PHP, etc. Then you should've able to find guides of various skill levels from there.

It depends on your programming experience. What language do you code in? Java's a good mainstay and easily migrated to if you are used to c or c++/Csharp?

http://ruby.railstutorial.org/ruby-on-rails-tutorial-book