A comparison of client-side web application frameworks
lispservice.posterous.com
lispservice.posterous.com
SproutCore seems to be in the lead at the moment.
Technologies like flex / silverlight / javafx / open laszlo use compiled binaries to run their applications via a browser plugin (flash, java vm, silverlight vm).
The other products in the heavyweight category utilize HTML / Javascript and don't require plugins. That's a big difference that this person seemed to miss...