On a worldwide scale, it is even a different thing. You can't simply replace coal with nuclear energy worldwide, even if you were absolutely convinced that nuclear energy is safe when properly used and you have a concept for the nuclear waste produced like shooting it into space. Because many countries are just too instable, poor and iniffecient to consider building a nuclear plant. It wouldn't be safe at all. Also, don't overestimate the availability of uranium, which is estimated to only reach till 2080 (depends on who you ask probably).