80 (i.e. along the shore in Berkeley) is really bad quite often, but you could possibly skip most of that. If you can avoid that, it's not too bad, although the 880 parts in Oakland (due to port/construction traffic) can be bad.
I wonder if, as "Oakland becomes the new Mission", if we'll see more of the tech giants sending shuttles up to East Bay. I know Google has at least one going to West Oakland, but Facebook does not yet.
Another annoying thing about 880 is the trucks and general narrowness. It is technically 45mph but people do 70-80. I hadn't had an accident there, but it kind of sucks vs the rest of 880.
You are aware that a lot of the Oakland/emeryville areas near 30th and such are pretty gangster, right? My friend had a loft there and I kept showing up at her buyer while the cops had the block shut down to serve a high risk warrant.