I've currently got BTSync dealing with a bunch of "non-private" data, and EncFS (and BoxCryptor on OS X) encrypting the more private data I'm syncing with BTSync.
I'm still "trusting" the BTSync app not to mess with my machine(s) in unexpected ways - but I have to trust every application I run to do that, Photoshop or Firefox are just as capable of "sending my data so someone else on the sly".
One thing I'm realy liking about the BTSync/EncFS setup is that I can have machines I consider "less trustworthy" to sync/store EncFS encrypted data without having EncFS/BoxCryptor installed or needing the keys. I'm happy enough for a spare machine at work, where other people might have physical access to it, to store EncFS encrypted blobs for me. I'm confident enough that's secured against pretty much everything up to federal law enforcement or nation state level snooping.