> within the academic discipline in question.
This is a nit pick, but all the examples you gave are of people who actually changed the world, not just some sliver of academia.
That said, changing your sliver of academia is likely to imply changing the world if you're in certain areas of math or science or engineering.
The only time when you can change your sliver of academia but not change the real world, is when your sliver of academia does not contribute to the real world, which is (unfortunately) common, particularly in the humanities. (Which is sad, because we actually really need good humanities study/education in order to build a good world.)