Not all of the advice applies, of course, but there's a lot of good advice on making a good workspace and keeping yourself motivated. I've certainly noticed after working alone that there's a lot of implicit encouragement merely from working near other people, and this makes working at home harder than the same work might otherwise be. That's part of the reason why many prefer to work from cafes or worker/hacker-spaces, I think. Motivation is contagious.
(The positive flip side is that working from home removes a certain set of distractions that might otherwise be bothersome, and gives you more fine-grained control over the distractions you have in general).
Lots of authors use funny setups to transition from home-mode to work-mode. Some people build extra doors in their house so they can "leave" their house and "enter" an office that is sealed off from their house, but is otherwise the same building. One author (Roald Dahl?) worked from a bunker.
That being said, its probably a bad idea to get hung up on the idea of perfect working-from-home conditions. Per E. B. White:
"A writer who waits for ideal conditions under which to work will die without putting a word on paper."
Some similar important words from Tchaikovsky, which I found especially relevant to working from home:
Do not believe those who try to persuade you that composition is only a cold exercise of the intellect. The only music capable of moving and touching us is that which flows from the depths of a composer’s soul when he is stirred by inspiration. There is no doubt that even the greatest musical geniuses have sometimes worked without inspiration. This guest does not always respond to the first invitation. We must always work, and a self-respecting artist must not fold his hands on the pretext that he is not in the mood. If we wait for the mood, without endeavouring to meet it half-way, we easily become indolent and apathetic. We must be patient, and believe that inspiration will come to those who can master their disinclination.
I think motivation is under-stated in its importance when it comes to working from home. Even if our work demands little distraction, we're social creatures, and we've probably all had days where its hard to even open up the editor.
It's important to stay positive and stay at it. As Joel said, "We just have to come in every morning and somehow, launch the editor."[1]
[1] http://www.joelonsoftware.com/articles/fog0000000339.html