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Prions absolutely terrify me. Primarily because they are so difficult to kill, er.. destroy. They are basically the zombies of infectious particles.

http://www.nature.com/news/2008/080701/full/news.2008.926.ht...

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Alzheimer and other dementia are also probably the result of an a priori prion-like phenomenon.

I'm interested to see someone else take this stance. A large part of my PhD is based on ideas relating to this, but it's not a (currently) widely held train of thought. Are you involved in this area at all?

I recall an article a year or so back that implied that Alzheimer’s could be transmitted between mice if certain proteins were moved from a ‘sick’ mouse to a healthy one. I cannot recall the authors or even the journal, but I am sure you read it, if it was of relevance in any way.

Here's the paper: http://www.jneurosci.org/content/33/3/1024.full.pdf?sid=c461...

Open-access version: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575082/

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