My first impression that Microsoft perhaps hadn't thought the whole Windows 8 UI through was actually gained at a Microsoft conference. A chap sitting in front of me was attempting to use the Windows 8 tiled interface on a laptop balanced on his lap - he reached out to do something, touching the screen and managing to knock the laptop off his lap onto the floor.
I like a lot of Microsoft products (Excel, Windows 7, Visual Studio, SQL Server, Dynamics AX) - so I'm not a Microsoft hater by any means but I do wonder about their judgement in this particular area.