I personally think that we are at a point that we can make some significant advances in miniature engineered things that interact with the human body (and everything really).
Miniature robots in our bodies (or just blood, I don't know that much about the subject) that we can program or have upgrades for, or just monitor. They could clean cholesterol, monitor numerous levels/vitals, prevent clots, and anything really. They could be especially useful for preventing overdose or sudden onset diseases. I can imagine a text in the future to people, "Warning, your Blood Pressure is abnormally high, here are some tips to help you lower it." or "Blood Alcohol Content is currently at .10, you are not legally allowed to drive."
Yes, it's dangerous. Yes it will probably be possible to easily engineer something that will kill all of humanity, but those are problems we will have to make safeguards for.
The clip is stomach churning. Don't watch it if you're eating.
I'd go for quantum computing
What would be the applications for real-time NLP and translation? I can't think of anything beyond being able to have the words appear on the screen faster or actions being preformed half of a second faster.