joshkaufman's comment made good points:
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In my experience, pretty much every business closes for one of three primary reasons:
1. The business runs out of money and/or available financing.
2. The owners decide the business isn't returning enough to justify further investment of money or effort.
3. There's some irreconcilable difference of opinion between owners, leading to an impasse on a critical decision and dissolution of the business.
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