I was a consultant for 3 years during most of which I traveled 5 days a week. It wasn't exactly the case but I can say I lived in hotel rooms with a carry-on suite case for those years.

I realized that all I need for my life can be packed into a carry-on sized suite case and I had perfectly enough space in a hotel room. I will never feel the need for 5 bedroom house so that I can have a man cave, a home office or "an entertainment room" and a whole basement load of stuff.

There is this great movie about simplified life (yes there was also relationship and George Clooney) - Up in the air.