Ask HN: What podcasts actually teach me something?

I've never listened to podcasts in the past but I've started to enjoy using them as gap fillers. I've been looking trough HN and reddits tech podcast topics and while there is a ton of material most of it is rather disappointing.

5by5 for example has some great stuff, but 9 out of 10 of their podcasts are either about Mac and iPhone or an interview of some guy I never heard of who talks about how his dog helped his career or the color of his wallpaper.

I don't mind off-topic talk, but I like it to be informative in some way.

The Changelog talks about new and trendy projects on github or even adresses those developers directly. I like that.

Is there stuff like this out there? People talking about new projects, libraries, best practices, design aspects, hardware, web development. Stuff that makes me think "Good to know, I'll try it".