There was a post on HN jobs a little while back about a startup looking for a "front end guy" which reiterated several times throughout the post that they "need a guy" and if "you're the guy" to contact them.

The job sounded great otherwise, and was definitely one I would have been interested in, but I felt immediately disqualified and annoyed.

Normally these types of things don't bother me and I often think people read too much into things, but for some reason, that one did. Maybe it was the casual nature of the writing. It made it seem more personal, which, in turn, made it seem like the author was making it clear that they actually weren't interested in hiring women, that they legitimately felt as if a man was needed to fill the role properly, or that the idea of hiring a woman was so foreign to them that it hadn't even crossed their minds.

It was very off-putting.