Specifically for me, pipeline fits into django's collectstatic way of doing things. And because of this it works fantastically with django-storages as well. My projects are set up so that `python manage.py collectstatic` trawls all my apps static folders, compiles everything if required (r.js, sass) and uploads any changes to an S3 bucket. And in development it compiles over the wire (except r.js, we let requirejs do the async loading thing in development).