It's interesting that Ron Gilbert originally wanted to base SCUMM on Lisp: http://www.pagetable.com/?p=614
Of the few SCUMM script examples I've seen, I can't seem to understand what Gilbert means when he says: "It did things Lua could never dream of." The ability to control a C64 from a UNIX box? That actually sounds a lot like Naughty Dog's GOAL: https://en.wikipedia.org/wiki/Game_Oriented_Assembly_Lisp