There have been several pieces (from classical to classic rock) that have actually caused me to break out in tears. Not teary eyes mind you; gushing waterworks at specific resolution points. Amazingly, this is reproducible, but the severity of the effect depends on my mood. After reading this, my best guess is that this is tied to an especially intense release of dopamine. My maternal grandfather shared this peculiarity and both of us have had awkward moments where we try to explain that we are quite OK -- "it was just the music" (an explanation often met with puzzled expressions).