You didn't like his answer of "I worked my ass of to get here"? Is it that he didn't acknowledge the role of good luck or do you honestly think he didn't work to get where he is at?
(I don't know much about the comedy business, though...maybe there just aren't many people who put in as much time as Louis C.K.)
There are plenty of funny comedians who don't make it big (Eddie Pepitone comes to mind) and work hard, but you can't describe how to get lucky, all you can describe is how to not fuck up opportunity.