There are lifestyle considerations too. Academic work year, no crazy work hours, etc.
Working all days of the week is incredibly common.
And, unfortunately, crunch time specially near major conference deadlines is almost becoming the norm. Of course, the focus on publication is another problem related to that.
Many research positions are in industry, or are postdocs or non-tenure track. Besides the fact that many countries don't have anything similar to tenure.
Also, not everybody on tenure track reaches it.