I would highly recommend chicken scheme for most projects. It isn't as mature as other ecosystems, but it is getting there fast and is already quite mature and practical. I've used it to build multiple web apps/sites.[0][1]
Learn more about the features it provides: http://wiki.call-cc.org/man/4/Getting%20started
An index of the many libs it supports: http://wiki.call-cc.org/chicken-projects/egg-index-4.html
Why another lisp? http://wiki.call-cc.org/man/4/faq#why-yet-another-scheme-imp...
Getting good performance: https://news.ycombinator.com/item?id=5381472
[0] http://thintz.com?hn=t [1] https://a.keeptherecords.com/demo