its simple. if my wife doesn't take her medication she spirals down into a deep depression. it doesn't matter if she's at (what everyone would say) the happiest moments of her life, she's going to get depressed. now flip that when she's taking her meds, she is able to handle and snap out of it if things aren't going so well like any other normal person would. She still gets sad and feels bad, but _she gets over it_, where as if she's off her meds, _she doesn't_. i'm involved with this and see it on a daily basis.