Widespread use of the currency is troublesome if it's possible for anyone to have reasonable odds of forking the chain. If it's possible for a mass panic to reverse transactions, it's not as reliable.
If Asia (4 billion people), banking institution (US federal debt = ~23% of world GDP), or a social group (Catholicism: 63% of the Americas) buys a bunch of stuff then decides, en masse, to revert to an earlier blockchain, it could drive instability. Large groups of people sometimes do unpredictable things (Gangnam Style: 1.4 billion views).