Yes, really - but it is a matter of taste as tsumnia says in the sibling comment
In Monopoly, I can go bankrupt. In Nethack, I can (and often do) die. In Super Mario Bros 1, I can lose all of my lives. In football, I can get knocked out of the Champions League (by a red card).
In all of these cases, the fact that I can "lose" creates meaning - I care more about the outcome and I appreciate my achievements more. And one never loses everything - the skills stay with you. "Next time I can do better."
Counterbalancing, for a different mood: works like Ocarina of Time are still great, but they sit separately - they're about the journey, not about the achievements.