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Safari's desktop share is somewhere between 5.5% and 15.5% depending on whose stats you trust:

http://en.wikipedia.org/wiki/Usage_share_of_web_browsers#Sta...

Is it crazy to consider that significant?

I personally consider it not major but significant, not just due to market share but also because it's the default browser (and shares its inner components with applications leveraging WebView) on a certain platform. Therefore it's a prime target for establishing a foothold on that platform.

Mobile Safari was not in the list offered as targets if i read that right..

Safari actually has 60% of mobile web usage.

Source: http://tech.fortune.cnn.com/2013/02/01/apple-android-market-...