I'm surprised how well AngularJS has worked for us.

Currently, we're using it for the shopping checkout page and also for the merchant dashboard. The dashboard is all driven by AngularJS (using $resource/$http api calls). The checkout page is more like Twitter, in that we preload data in the DOM when it's rendered, but there are API calls via AngularJS to create the order, check quantity, etc. These pages are actually served directly from our CDN.

As far as how it's worked for us. We've actually rewritten our dashboard and checkout page twice, and it look some getting used to on how to structure our controllers. Getting used to writing directives instead of using jQuery and doing DOM manipulation in our controllers also takes some discipline, because it's just way simpler to drop some selectors and event bindings/triggers in your controller.

The way AngularJS encourages you to keep any dom manipulation out of the controller and to think about reusable directives has really helped for readability and maintainability of the code base. We're consistently surprised how quickly we can implement features because of AngularJS. We've actually said, "Wow, that was easier than I was expecting" quite a few times.

However, there are some hurdles. $http doesn't support file uploads, the stable release doesn't support custom http headers with $resource, only one ngView, etc. That said, I still would not hesitate to recommend AngularJS.