I've certainly experimented with iTerm2, but, except for radically better copy+paste performance of large blocks of text, nothing about it really pulled me in. Perhaps I should spend more time with it.
To your points - Tabs are cmd+shift { }, which feel very natural on my keyboard given the location of cmd+shift - you 'chord" thumb+little finger and then switch windows with your right hand (or maybe it's just entered my finger DNA).
Windows Switching is the OS X standard Cmd+`
PageUp/Page down are just your standard Fn+Up/Down - but, I'll admit I just normally use the touch pad it's so fast, particularly with two+finger drag + acceleration.
The loss of the middle put-on would probably be painful - but I've never had one, so no huge impact to me personally. (Copy/Paste are, once again, touch pad reflexes that I do constantly).
But - with all that said - I really should spend more time with iTerm2 - lots of people rave about it. Time to give it another try.