I am also a GAE-user, I have had no problems like the OP. But I start to miss a fundamental feature, sockets. I have worked around it by using other services and polling.

Maybe wrong forum, but is there any infrastructure templates for setting up a scalable web/db/loadbalancer/memcached for a simple tradional webservice, in my case a game?

I want to be able to sleep at night, and easily scale up by adding some more machines in case of higher load.

I could use denormalized myslq/postgre or mongodb for speed. Preferred language is Python (or maybe c# or java).

Any ideas?