On the Python 3 subject, I'd be highly interested in seeing if there any performance wins by switching your Django deployment to Python 3 over something like Python 2.7.
* If you use decimal module, you will benefit from the serious speed improvements (http://docs.python.org/dev/whatsnew/3.3#decimal).
* The memory usage of strings is slightly lower (http://docs.python.org/3/whatsnew/3.3#performance-and-resour...).