It was certainly disconcerting to see the failure of a component that was supposed to be the core of my infrastructure. Cloudfiles just moved out of beta about a week ago, and for growing pains the outage was pretty long.
According to their status updates, data integrity was never at stake, just availability. CDN files were always accessible.
I'm relieved to see that the Jungle Disk integration seems to be to blame for this, since this hints at a one-time peak load event rather than an overall infrastructure failure.
I think the ease of use of the CDN and low latency of delivery for many small files is a big win. Is anyone else here (thinking of) using them?