"In Lisp, there is substantial fragmentation on how do things like GUI and Networking, and often no clear winner"
Is there a clear winner for GUI in Python? GTK, Qt, etc. Python also has quite a few networking libraries; networking in today's world is more than mere sockets.
"SBCL seems to be the de-facto FOSS implantation"
Meh, GNU Clisp is pretty relevant, and a lot of people are using Clozure. CMUCL also remains relevant, if only because of its useful extensions (SBCL is a fork, and dropped many extensions like Motif support).
I think what CL really needs is an update, a CLtL3 that adds support for modern features. Modern Lisps like Clojure and Racket do not have many of the constructs that make CL great (which is not to say that Clojure or Racket are not great languages, but they are missing some of the nicer CL features).