I believe it would be easier for someone to reply if she (you) can identify at least some areas she can be of value, has any type of experience or even interest alone. Usually startups are about optimizing value each one adds to the total. For some ideas of areas/skills she could be helpful look this post from today: http://news.ycombinator.com/item?id=5210184 Not that she (or someone else even) has to master all items listed there, but shows what some startups may be looking for (or need help with).