Mine is going to be based on the "Wages of Wins"-emphasized stats of FG%, FT Attempts, Turnovers, and Offensive Rebounds.
If you want to get a little more hardcore, check out HN user lance's post about using Logistic Regression Markov Chains for your bracketology:
http://blog.weatherby.net/2009/03/using-lmrc-to-pick-ncaa-to...