I started to telecommute three days each week (office is ~ 2hrs from where I live) right after Thanksgiving in 2012 and am still adjusting to the lifestyle.

The biggest takeaway - so far - is that successful telecommuting is determined just as much by the given task as the person. I serve as a mixture of business analyst/developer/test coordinator/project lead/cat herder for my project team. Some tasks are easy to coordinate via e-mail/IM, screen sharing and conference calls (like scheduling, status updates, walkthroughs of protoypes). Being able to power through functional and technical specifications is a tremendous bonus of working from home. When it comes to gathering requirements, acquiring feedback and dealing with politics, however, it's really much better (for me) to be in the office.