If you want to run your own PyPI internally, here's a very simple PyPI server (~150 lines of Python) that I wrote: https://github.com/steiza/simplepypi
What I've personally been looking for is an easy to setup caching proxy for PyPI. Something that is pip-compatible and serves files if it has them but will also fetch and then store packages if it doesn't. That way you could build up a collection of 3rd party packages over time, without having to explicitly manage it.
It probably wouldn't be hard to roll my own with a reverse proxy but it never gets moved to the front burner.
http://djangopypi2.readthedocs.org/en/latest/
For now though we'll probably just create a new git repo with a folder full of source distros (tarballs and zips), as mentioned above.