I recently used http://www.shinywhitebox.com/home/home.html for this very purpose. I did a very simple demo of our application with me talking, merely for the purpose of showing a remote colleague what we were doing. Worked great.

If you go here: http://seankelly.tv/videos/tools-of-the-trade/ you'll see a great post about some good tools. This fellow created a nice cast of different web development frameworks that's become a must-see on the web. Might even post it here as a separate item for folks.