I would love to see cinematographers experiment with natural lighting for shots. Kubrick (in)famously did this in Barry Lyndon[1] 37 years ago. To do this he used f/0.7 Carl Zeiss lenses that were designed for NASA.
Nowadays we are far less limited due to the incredible light-sensitivity of modern image sensors. And if that doesn't work we can go for larger sensors, which would still be far cheaper than doing the same with film.
I have a feeling Kubrick would be having a field day with current tech and would have been one of the first supporters of 48Hz.
[1] https://en.wikipedia.org/wiki/Barry_Lyndon#Cinematography