Why do you think it causes depression more than the Roche data suggests? The studies about depression and suicide are similarly inconclusive: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1463189/
Is the data from the Roche lawsuits available? I'd like to know what evidence is resulting in these multimillion dollar IBD/Crohn's cases.
I took two courses of Accutane after reading several research papers and population studies of side-effects. I came to the conclusion it's safe, and would be interested in seeing any data that shows otherwise.