Doing something basic on a mac like Copying (Ctrl + C) and Pasting (Ctrl + V) had to be done with ⌘ Command. So instead of using my pinky in natural resting by simply shifting my palm down which I was used to. Using the ⌘ Command, I had to use my thumb instead and it was always a weird shift. Having used Windows most of my life, I always had to look down to make sure I was on the right keys on a Mac.
I've tried a few times to go back, but its always been such an unnatural feeling that I just avoid it now like you do.