I was in Florence, Italy earlier this year and had a few minutes of waiting around when I remembered one of my best friends (who I hadn't spoken with in 15 years because life) had gone to Italy for some artistic endeavors years ago. I couldn't exactly place him, but found some tenuous links to a studio that was only a 5 minute walk from where I was standing, so I took the chance and knocked on a random door on a random street - and voila.
A friendship that started over 30 years ago in California was rekindled, like lighting a dry pine tree on fire. It's been amazing, and we're working on some cool projects together.
Get out there. Take chances. Knock on doors, say hi, introduce yourself. Who knows what could happen.