Tektronix sold Smalltalk workstations [1], you could run Lisp on them as well. You may have been able to run Smalltalk-80 on a Xerox Daybreak which was a fair bit faster than an Alto.
The first JIT was written by L Peter Deutsch for Smalltalk targeting the 68020.
[1] https://www.mirrorservice.org/sites/www.bitsavers.org/pdf/te... [2] https://en.wikipedia.org/wiki/Xerox_Daybreak