Yes, it's different. We already had projectiles when guns were invented, and guns were different too. Further shifting the balance of power to those with thousands of GPUs is different.
My comment was focused on the original comments insight that AI will use humans to try to end other humans as it's imo nothing more than a change in who is doing it than a difference in what's happening. In that scenario the balance of power is in the hands of the AI and not the people who control, or I guess controlled, the GPUs.