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Ok, let me rewrite.

The acceleration I feel is in the head-feet direction, so it's relevant for the muscles, since their fibers seems to be aligned in this direction. The centripetal acceleration would be perpendicular to the usual muscular development, so... in this scenario, would that place still work for astronaut's body?

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No, it wouldn't. There is no meaningful way for gravity to be "perpendicular to the usual muscular development". You would orient your head-foot axis to match the direction of the acceleration you feel. Floors and walls in a space habitat would be built in that orientation. Doing otherwise would be just as stupid as lying horizontally on Earth and then complaining that gravity goes the wrong way.

Oh, I see. So it was more of a question that I could not observe how this would be built than its effectiveness per se. Thanks for clarifying.

On a side note, they mention one equipment like that in this novel(a hell of a good scifi): The Martian, by Andy Weir. Available for free online, really funny.

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