You say that like its a problem.. its a formidable solution!
Has worked for me for many years now: Just fail2ban-style block (groups of) relays that attempt to send an unsubscribe-link destined for a mailbox that never ever subscribes to anything. Those malicious-compliance folks add these unsubscribe links everywhere because they determined that its a cheap method for reducing blocks. That makes them reliably stand out whenever they hit strictly human-to-human mailboxes that simply never have any reason to "unsubscribe". Its like a honeypot, and all it took was a strict policy about what a tiny fraction of mailboxes can and cannot be used for.
Spammers are quite proficient at using authentication, whereas legitimate users are stuck in the 2000s wondering why their forwards don't work anymore.