If I was to point at the absolute fundamentals, I'd say the open trade in the 1800s that caused many countries to rely on external supply chains leading to mass urbanization and hollowing out their agriculture created countries that were far less self sufficient.
With millions migrating away from the farms and working the land, moving to the cities, many countries were less self sufficient and it created an extreme imbalance and vulnerabilities. World War I might not have happened without that.
The economic issues combined with World War I was ripe ground for social movements which in the past were not always existential. When Russia was taken over by communists, they began to weaponize communism around the world. Any country that was undergoing hardship was a prime target.
Japan and Germany both suffered greatly from the 1800s mass urbanization with a weakened agricultural sector and when trade began to shut down in the 1930s to protect local economies out of fear not doing so would create an opportunity for the communists, this crushed Japan and Germany.
It would be fair to say then that there was some wisdom to globalism, but there was also some ignorance and it was not well managed. Yet, had communism not been the threat it was, global trade may not have receded as aggressively as it did.
So Russian weaponized communism, in full understanding of what communism actually is and how it operates in brutal destructive ways to destroy a society, combined with international imbalances caused by poorly managed trade in a rapidly industrializing world is a pretty good summary of what I see as the real causes of World War 2.
I'm not accurate about everything and I've made mistakes even in this thread which I didn't notice until after the edit option was gone, but I do make an effort to identify mistakes when I find an inaccuracy. Broadly, I think all the critical things I've said here will hold up as I haven't found convincing counter-arguments. If high quality counter-arguments are presented, I'm not closed minded and will consider them.