But there's another point in the tradeoff space. One of the explicit design decisions in Fearless SIMD is to support "downcasting," or specialization to a specific microarchitecture. At least for the kind of problems I've worked on, even when you're doing something fancy with arch-specific permutations or what not, the majority of the operations will be pretty vanilla, and can be expressed well in the portable subset.
So you can think of a library like Fearless SIMD as enabling your extreme optimization use case, just more ergonomically.
Of course, this depends on LLVM compiling intrinsics to assembly efficiently. That hasn't always been the case, and is not perfect now (a number of issues have been filed against rustc and LLVM while developing Fearless SIMD), but is pretty good.
As always, though, you do have to measure performance, and I frequently look at the assembler output to double-check that it's doing the right thing. The day of "fire and forget" portable SIMD has not yet arrived.