There was some talk on here during Covid about the feasibility of making all structures up to BSL4 standards. Seems kind of nuts, but it would certainly contain a lot of biosafety threats. With AI it now seems borderline urgent.
(Speaking personally, my home indoor air quality is now awesome and I love it. Wish it hadn't taken a pandemic to clue me in, though.)
And so the question of what effects getting rid of several-yearly respiratory infections would have on our health and the development of children remains open.