This is vague and doesn't explain anything. Can you share any references that communicate what you're thinking about?
This is vague and doesn't explain anything. Can you share any references that communicate what you're thinking about?
It became something of a panacea nutrient, recently around COVID.
And too much D3 without calcium supplements make the body use the calcium from it's bones !
lots of vit D without the NO there to improve vascularity makes the arteries hard
~40% of people don't get enough vitamin D [1]. It's not useful to categorize it as some trend, based on people just not following general recommended dosing (with more precise dosing depending entirely on personal sun exposure and skin color).
edit: As an office worker, I take 10k IU per day when I'm entirely indoors (most of the time), but vary it based on sun exposure. I based this on recent studies, and have my doctors approval with an exactly center-of-the-nominal-range vitamin D serum level.
0: https://drink4good.com/can-drinking-too-much-carrot-juice-tu...
These numbers seem high to me. The 75 nmol/L (30ng/L) is not really a reliable value. It was published in a research that raises many questions due to conflict of interests.
Hence the
> ~40% of people don't get enough vitamin D
becomes:
> ~40% of people in the USA don't get enough vitamin D according to Dr. Holick
Where I live the norm is 20 ng/L and if we apply that, then the shocking 40% becomes more reasonable 10-15%
How did they come to this?
Seems like a reasonable measure would be to look at a native person, from ones lineage, having a relatively average pre-industrial day.
If lineage doesn't matter, and all humans are the same, you could probably just go sample some tribe members that still lives mostly outdoors, outside of developed society.
And, regardless, I'll listen to my doctor.
Clearly he made a lot of money publishing that research. And people who paid him also made billions. But let's focus on the rest of the world that didn't increase the norm that works by 50%
I don't want to go into this debate. The cited benefits of Vitamin D have to do with Calcium and bones. This is just absurd to me. Do people in Europe have brittle bones? Those 40% with alleged Vitamin D deficiency have issues with Calcium and get bone fractures every other day?
There is no substance to discuss here, sorry.
More to the point, since Covid Researchers have posited that Vitamin D plays a critical role in preventing respiratory infections, reducing antibiotic use, and boosting the immune system response to infections. Vitamin D is important in regulation and suppression of the inflammatory cytokine response, which plays a role in the severe consequences of COVID-19 and ‘acute respiratory distress syndrome’ associated with ventilation and mortality in COVID-19. Vitamin D also helps the respiratory tract produce antimicrobial peptides that can lower viral replication rates.
RAPID EVIDENCE SUMMARY: VITAMIN D IN COVID-19 https://assets.gov.ie/static/documents/rapid-evidence-summar...
The causal role of vitamin d deficiency in worse Covid-19 outcomes: implications for policy and practice development https://repository.rcsi.com/articles/journal_contribution/Th...
Coronavirus disease 2019 and vitamin D https://pmc.ncbi.nlm.nih.gov/articles/PMC10277257/
Vitamin-D and COVID-19: do deficient risk a poorer outcome? https://www.thelancet.com/journals/landia/article/PIIS2213-8...
Am I talking to AI?
Roughly 20% of the UK population (1 in 5 people) is clinically deficient (<20 ng/mL). Similar in Ireland.
If we extrapolate slightly from 'clinically deficient' to 'subnormal' then 94 % of children, 94 % of teenagers and 90 % of adults on the island of Ireland have inadequate vitamin D intakes. This is because the Sunlight UVB radiation needed to make vitamin D is only available in Ireland during the months of April through October.
For us and the other latitudes which experience a ‘vitamin D winter’ that stretches from the end of October to late March, almost everybody in Ireland needs a supplement of vitamin D and 15 µg (600 IU) is recommended on a daily basis.
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And, now you've discovered why Europeans have light skin [1]! And, why supplementation is suggested for those with dark skin [2] living in regions with light skinned natives!
[1] https://www.science.org/content/article/how-europeans-evolve...
> But the likely explanation for the pigmentation genes is to maximize vitamin D synthesis
[2] https://www.cooperinstitute.org/blog/african-americans-at-gr...
What does the color of skin have to do with the normal amount of a vitamin in blood?
Skin tone merely regulates how much you end up producing. Just because your skin is bright doesn't mean you need less of a vitamin.
I'm sure there is some variance in this, but I doubt it's swinging between 20 and 30 ng/mL
[1] also covers evolution of skin tone https://en.wikipedia.org/wiki/Vitamin_D
Some levels are normal, some are low. "Skin color" affects production as you pointed out, but that has literally nothing to do with what we are discussing.
Sunlight UVB radiation needed to make vitamin D is only available in Ireland during the months of April through October. This is due to our geographic location 52o - 55o North and means that Ireland experiences a ‘vitamin D winter’ that stretches from the end of October to late March.
Currently, 94 % of children, 94 % of teenagers and 90 % of adults on the island of Ireland have inadequate vitamin D intakes. Therefore, almost everybody in Ireland needs a supplement of vitamin D and 15 µg (600 IU) is recommended on a daily basis.
N.B. In the early 2000s, over 20 cases of rickets (a weakening of the bones caused by severe vitamin D deficiency) in infants and toddlers were reported in Ireland.
If you don't have a primarily fish based diet or spend hours under direct overhead sunlight every day without a shirt on, you're probably deficient as well.
> Recommendations to Obtain Adequate Amount of Vitamin D.
> Sun exposure to the face, arms, hands, and legs without sunscreen for 5 to 30 minutes at least twice a week or more between the hours of 10 am and 4 pm
Source: https://pmc.ncbi.nlm.nih.gov/articles/PMC8299926/
Now that's for most people: if you live in Alaska then during the winter maybe you need a litle more or something ... but the point is most people just need a little sun, < 30 minutes twice a week.
That study also claims 12-20ng/mL 25-hydroxyvitamin D is sufficient. My doctor says the post-COVID studies suggest 75ng/mL is closer to optimal, and <30ng/mL had been considered deficient for about a decade before COVID.
Personally I had no problem hitting 20ng/mL through sunlight alone and I'm pretty fair skinned but live somewhere sunny. But I haven't been able to get anywhere near 75ng/mL even when I've made an effort to increase vitamin D through supplements and exposure to the sun.
In Calgary, it's almost half the year that you basically cannot rely on the sun at all for vitamin D.
basically any patient he did blood work on, that was an office worker, was moderately or seriously deficient.
Overdose has been observed at 1,925 μg/d (77,000 IU per day). Acute overdose requires between 15,000 μg/d (600,000 IU per day) and 42,000 μg/d (1,680,000 IU per day) over several days to months.
Unless, as mentioned, it had some traction as a cure all around the time of COVID.
This happens periodically and is again happening with vitamin C (which, whatever, getting to any dangerous amount might be physically impossible).
A pretty standard bottle of Vitamin D at 10k IU is 60 capsules/pills/whatever. That's a 2 month supply.
To hit the toxic eventually (77k IU) you would be going through a 2 month supply every ~7 days. To hit the acute toxicity in days or weeks (low end 600k), your going through that bottle every day.
However, every single time that someone mentions Vitamin D, people jump out of the woodwork about toxicity without ever actually bringing up just how much you have to take as if if you take the 400 IU capsule, going one IU over is going to kill you. I'm also pretty sure that a specific group of denialists shouldn't be counted as a reason to scream warnings from the mountaintops every time someone thinks about Vitamin D.
Sure. This is only going to be anecdotal and sparse examples, but this became a thing post-Covid, primarily as a "natural alternative" to vaccination.
Not just random people on random forums, Joe Rogan several times espoused the value of D along with other usual suspects:
"Rogan said he started feeling ill on Aug. 28 and tested positive the next day. He added he began taking his regimen the same day, which apparently included ivermectin, IV drips of vitamins D and C, nicotinamide adenine dinucleotide (NAD) that helps repair cells, and monoclonal antibodies. He said he felt fine the next day."
"Man Vomits For Months After Taking Vitamin D at Almost 400x Daily Recommended Dose"
https://www.news-medical.net/news/20220706/e28098Hypervitami...
https://www.sciencealert.com/man-overdoses-vomits-for-months...
Also unsurprisingly happened more often around this time with infants:
https://www.frontiersin.org/journals/pediatrics/articles/10....