I definitely think AI is going to change this. Astra is shockingly good at reverse engineering. I was working with a proprietary software library and I just asked it how some (poorly documented) function worked and it just went off and disassembled it without me even prompting. I asked it if there was a way of disabling some error checks and it went and found some undocumented functions (not in the header), disassembled them and figured out how to use them for me.
I didn't actually even give it the ability to run this code and it could still reverse engineer everything.