Yes.
Nvidia issues a commitment to a firm that lets an SPV raise money. Some of that is just M1 being transferred from one account to another. A lot, however, will be created through loans (new M1), commercial paper (new M3) and the like. Some of that will be pledged as collateral. On the other side of the equation, when the SPV signs e.g. a construction contract, you'll have builders taking out bank loans and issuing commercial paper, et cetera.
You can pay your taxes out of a checking account using money a bank created out of thin air that morning that the Fed won't even learn about until the evening.
> monetary aggregates are things that are theoretically equivalent to creating money, but I'm going to challenge whether it is proper to compare M4 activity to the fed balance sheet
You're absolutely correct in M4 being unequal to the monetary base and deposits at the Federal Reserve. But the moment you say the Fed balance sheet, you're conflating two things. The Fed has lent, in the past, against non-Treasury collateral (most famoulsy, mortgage bonds).
And if we're talking about money in relation to the real economy, you can't spend reserves at the Fed. There is debate on what the most "real" money is, but pretty much everyone agrees that a deposit in a checking account is more relevant to the economy than unspendable reserves at the Fed.